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NCATS 2020 ASPIRE Reduction-to-Practice Challenge (ASPIRE 2020)

Development of a Comprehensive Integrated Platform for Translational Innovation in Pain, Opioid Use Disorder and Overdose

Department of Health and Human Services - National Institutes of Health

Total Cash Prizes Offered: $2,875,000
Type of Challenge: Scientific
Submission Start: 11/30/2020 05:00 PM ET
Submission End: 02/28/2021 05:00 PM ET

This challenge is externally hosted.

You can view the challenge details here:


Key Dates:

  • The Challenge Begins: November 30, 2020
  • Submission Period: 5:00 PM ET, November 30, 2020 – February 28, 2021, 5:00 PM ET
  • Judging period: March 1-31, 2021
  • Winners announced: Spring 2021

For full details about eligibility requirements, competition rules, detailed judging criteria, and deadlines for submissions, please consult the NCATS ASPIRE 2020 Challenge Details page.


Total Cash Prize Pool:


Non-monetary Prizes:

All winners will be posted on the NCATS public website (


All details related to rules and eligibility are defined on NCATS’ ASPIRE 2020 Challenge details page. Only complete applications will be reviewed.

To participate:

  • Must follow all rules & guidelines listed on NCATS’ Challenge details page
  • Must be 18 years of age or older
  • May participate individually or as part of one or more teams
  • Each team’s designated lead must be a U.S. citizen or permanent resident
  • Must submit solutions by 5:00 PM Eastern Time on February 28, 2021

To win prizes:

  • Must be a US citizen or permanent resident
  • Agree to the eligibility rules and requirements listed on NCATS’ Challenge details page

Judging Criteria

Please review the official rules for the judging criteria here:

How to Enter

Each team must designate a lead who is a U.S. citizen or permanent resident and submits a solution on behalf of the team. The lead is responsible for all correspondence regarding this Challenge. Each submission for this Challenge requires a complete “Submission Package.” The Submission Package includes four required sections: cover page, plans for reduction-to-practice of the prototype, qualifications statements and references. All submission materials must be emailed to by the specified submission deadline date and time.

Submission Email:

Point of Contact

Have feedback or questions about this challenge? Send the challenge manager an email