NASA Vascular Tissue Challenge
A first-to-demonstrate challenge to create thick, human vascularized organ tissue surviving 30 calendar days
Type of Challenge: Scientific
Partner Agencies | Non-federal: Methuselah Foundation's New Organ Alliance
Submission Start: 06/13/2016 12:00 AM ET
Submission End: 09/30/2019 11:00 PM ET
Competitors will be asked to produce an in-vitro vascularized tissue that is > 1 centimeter in thickness in all dimensions at the launch of the trial and maintains >85% survival of the required parenchymal cells throughout a 30-day period. Tissues must provide adequate blood perfusion without uncontrolled leakage into the bulk tissue to maintain metabolic functionality similar to their in-vivo native cells. Histological measurement of the quality and amount of functional performance will be required to determine survival of parenchymal tissue. Teams must demonstrate 3 successful trials with at least a 75% trial success rate to win an award. In addition to the in-vitro trials, teams must also submit a Spaceflight Experiment Concept that details how they would further advance some aspect of their tissue vascularization research through a microgravity experiment that could be conducted in the U.S. National Laboratory (ISS-NL) onboard the International Space Station.
Centennial Challenges Vascular Tissue Challenge