This research plan proposes to use a biomaterial approach to address the challenge of reproducibility of retinal organoid culture This proposed study is sparked by the recent finding during the collaboration among Drs. Dong Feng Chen, Kinsang Cho (Schepens Eye Research Institute), Dr. Taching Chen (ophthalmologist of Taiwan National University) and Weifang Su, a seminal biomaterial scientist and Professor of Taiwan National University. Our goal is to develop a reproducible RO model to investigate the mechanism of retinal degenerative diseases such as glaucoma, interactions between retinal neurons and drug screening.
Solution for: NEI 3-D Retina Organoid Challenge (3-D ROC)
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